The project originates from an objective necessity, having in view the adherence of Romania to EU and the assuming of the involved tasks. A correct information campaign of the population regarding the application of biofuels is absolutely necessary. This campaign has in aim the use, at large scale, of biofuels and the population awareness regarding their use, which does not imply only costs but also benefices:

• a cleaner air which will be reflected in reducing the health budgets (by the decrease of the diseases caused by the environment quality, especially the respiratory ones);
• possibility to create new jobs (the production of biofuels, the construction of biofuels installation, service, biofuel quality certification);
• solving the waste problems: biogas obtaining;
• possibility of multiple uses of by-products.

• To elaborate modern methods which use high performance analytical techniques as: High performance liquid chromatography coupled with mass spectrometry (LC-MS) or LC-MS/MS, gas chromatography coupled with mass spectrometry (GC-MS) to determine the contaminants with steroid structure from different complex matrices, at nanoscale level;
• To identify and determinate the metabolites that can be formed due to the interactions of steroid compounds with the animal or human organism;

• study of accelerated degradation issue by corrosion aroused by electrical stray current appearing as effect of transport/distribution/utilization of electrical energy and the BA;
• experimental laboratory and in situ data acquisition (case analysis);
• building an active knowledge and data necessary to diagnose the current degradation state;
• implementing an intelligent diagnosis and active prediction system of SBA degradation state;
• elaborating of technical solutions, normative recommendations and methodologies regarding the design and execution of SBA having resistance with increased safety in exploitation and high durability in economical efficiency conditions.
  
  

• Founding a multidisciplinary network for promoting the research in the field of parallel robots for surgery;
• The promotion of the new found network in order to increase the international visibility of Romanian research in the field of parallel robots for surgery;
• The set up of a European network for participating in European research programs (for example PC7, Humboldt) and in European technological Platforms in the aimed field;
• The own multidisciplinary network integration in European research networks in the field of parallel robots with applications in surgery.
  

• development of the research capacities of ICIA by the development of the Laboratory of food quality control with a new component: the control of the chemical residues in food products;
• diversification of the research activity and the rising of the capacity to access the European funds

• The assessment of NAFLD and GD prevalence and risk factors in a large group of the population (about 10,000 subjects) - represented by hospital population coming from a large geographic area covering many counties from Transylvania - and evaluation of their belonging to the MS;
• The identification of non-invasive highly reliable methods for the confirmative diagnosis and staging of NAFLD;
• The optimization of the imaging diagnosis through mathematical modeling and image processing techniques;
• The creation of a complete database to enable the affiliation to the great European multicentric networks, within the 7 Framework Program.

• elaboration of an strategy on the implementation for biofuels on the Romanian market in order to promote the use of biofuels and other renewable biofuels for transport and agricultural mechanization specific fields;
• a plain regarding the biomass in order to promote the biomass for energy generation in accord with the assignments for Romania through the assumption of community aquis.
  
  

• Establishing the Centre for research, verification and certifying of biofuels quality;
• Improving the research capacity,  upgrading equipments by the acquiring equipments, hardware and software;
• Training the personnel from VERIBIOCOMB Centre;
• Elaborating the development strategy of VERICOMB for the next 3 years;
• Establising the access conditions for biofuels producers.
  
  

• development of ICIA’s research capacities by the development of a new field of the Environmental Analysis Laboratory: characterization and management of environmental wastes;
• enlargment of the research activities and increase of the capacity to apply for the European founds;
• the diversification of the research services offered by the Environmental Analysis Laboratory that is already accredited according to ISO 17025 : 2005 and offers competent research services in environmental protection field due to its large experience gained by the participation to numerous national and international research projects;

• developing an ecological, complex and complementary methodology for evaluation and monitoring of the quality of the hydrographical basin of Somes River, under the human factors influences, methodology which will help to amend the environmental quality for the sustainable development of the region;
• evaluating the quality of the hydrographical basin Somes will be made by study of the living organisms from the river (their structural and functional dynamic) from the polluted sectors (with cyanides and heavy metals), which will help the restoration and conservation of the aquatic ecosystems affected.
  
  

• The extension of the range of non-invasive clinical methods employed to analyze dental color by chromometric and spectrophotometric methods, as well as by computerized analysis of digital images;
• Establishing the staining capacity of certain restorative dental materials and of certain colorants used in soft drinks in the domestic industry upon dental structures;
• The production and the physicochemical description of a group of dental peroxide-based biomaterials intended for the treatment of certain clinical forms of dental color changes;
• They will be experimentally tested in the laboratory and the results will be compared with existing products at the moment on the market.
  
  

• Creation of an complex system of identification and nanoscale determination methods and techniques for some chemical residues from animal originated food products aiming to harmonize legislation from field of ensures the quality of food products with international legislation emphasis towards EU legislation;
• Accomplishing of an systematic study of influence of this residues n human health and correlation of products types with nutrition customs;
• Increasing the visibility of Romanian research towards the perspective alignment to European scientific community and accessing common research projects.
  
  

• To obtain some bioethanol-based ecologic biopetrols from white beet;
• To find the optimal white beet hybrids that will be used for obtaining bioethanol, successfully adapted to the pedo-climatic conditions of the region;
• To obtain bioethanol using a new and non-conventional technology of conversion and capitalization of the renewable sources of energy (white beet biomass);
• To draw up the obtaining technology for bioethanol and biopetrol;
• To set up the fermentation and distillation pilot plant.
  

The main objective of BIO-Q-NET is to create an adequate frame for connecting the Romanian biofuel research with the most representative European organizations and to develop a FP7 project proposal.

BIO-Q-NET aims:

• to establish a national and international (European) network in the field of assurance the biofuels quality;
• to promote the developed national network to enhance, at international level, the visibility of the Romanian research in the field of biofuels;
• to develop a European network in order to participate at the FP7 research programme and within the European Technological Platforms;
• to integrate the established multidisciplinary network in the corresponding European network;
• to elaborate a FP7 application regarding the assurance of the biofuels quality.
  

The study is direction through early diagnose and monitoring of child and teenager depression using some minimum invasive or noninvasive techniques by predicting the opportunity, security and efficacy of the antidepressive therapy following different biological markers and the evolution of the clinical frame but also by transposing the clinical results in practice in depressive children and teenagers.

Specific objectives:

• To elaborate the database;
• To implement the database;
• To finalize the database;
• To create the database and the presentation CD.
  

• performing a comprehensive psychological, genetical and biochemical evaluation of schizophrenic patients and to evaluate the effects of enzymatic cofactors supplemented treatment on some of these parameters.

The project’s main objective consists in accreditation extension of Laboratory of Environment Analysis of ICIA, for chemical analysis of organic pollutes concerning environment quality (soils, water and air) by chromatographic and spectrometric techniques.

Measurable objectives:

• Studies concerning fundamental analytical techniques: gas chromatography, GC-MS couple, IR spectrometry, applied in EU laboratories;
• Enhancement of technical capabilities by acquisition of performant instruments;
• Employee training by participation in various training courses, required by SR EN ISO / CEI 17025;
• Evaluation of testing methods performance, sample trials on certified reference materials and reference materials;
• Implementation and validation of new methods, evaluation of measurement uncertainty;
• Development of new specific trial procedures for tested methods and user guide for new instruments;
• Internal audit for demonstration of implementing the new methods;
• Development and implementation of corrective and preventive actions;
• Accreditation of Laboratory of Environment Analysis of ICIA by Romanian national accreditation institution, for the new methods.
  

• Arsenic sources definition;
• Defining the immobilization mechanisms in soils and superficial geological systems;
• Study of the water dynamics, as main vector of the arsenic underground pollution;
• Investigation of the mobilization processes and arsenic transfer from soil and rocks towards underground waters;
• Assessment of the risk induced by the exceeding arsenic from drinking water on human health.

• establish the connexions between the heavy metals exposure of some population groups from Romania with the health state (morbidity) and the cancer risk.

• microbiological hood with vertical laminar flow, 2A class, homologated, transferred to the cofinancing beneficiary, destined to provide protection for user, environment and for the biological products processed against foreign particles and biological contamination.

• promoting the access to work for persons who are disadvantaged because of severe mental illness;
• assessing the influence of cognitive and social rehabilitation over finding a job, over hospitalization rate and over quality of life indicators;
• promoting social inclusion;
• fighting discrimination and social exclusion by means that sustain and complete the national strategies and policies regulating employment;
• raising the visibility of Romanian research in promoting advanced techniques destined to ensure the basis for participation in the European consortium.
  

Until nowadays, it was described and used an important number of perforator flaps, transferred by microsurgical techniques, but only a small number of local perforator flaps was used in clinical practice; or it is well known that a like with like reconstruction, the use of local resources is the first choice. Our experience acquired by performing more than 100 local or regional microsurgicaly non-microvascular pedicled perforator flaps, microsurgical harvested but without microsurgical anastomosis, with good results and minimal morbidity, has determined us to find new perforator vessels all over the body, able to assure the better surviving of those flaps.

• decreasing the impact upon the quality of life through complex mechanisms (social and economic) based on the quality assessment of environmental factors-water, in extended urban areas in central Transylvania (Cluj, Mures and Salaj counties);
• optimizing the prevention mechanisms by increasing the efficiency and creativity in the public administration educational systems in the areas in study located in midland Transylvania;
• promoting a complex program for controlling contamination with carcinogenic substances (THM) in order to ensure environmental quality as well as health and safety for the citizen in accordance with the European strategic priorities for environment and safety;
• organizing, development and consolidation of partnerships in the domain of ecology and environmental and human health protection, for the purpose of research development and promotion in accordance with the European environmental requirements.

• to develop an informational system and to create a national agro-tourism instrument in order to present agro-touristic virtual environments, allowing tourists from all over the world to use it.

• Manufacture of ecological biodegradable products for achieving packaging and safety items;
• Replacement of synthetic raw materials with biodegradable polymers;
• Replacement of packaging and protective plastic items with similar products from biodegradable materials.
  

• to analyze the mechanic and elastic properties of the new biopolymers synthesized and their comparison with the polymers used as standard compounds (polyvinyl chloride, polyethylene or polyurethanes);
• to study the properties of degradation and biodegratation of the new synthesised compounds in accordance with the foresights of ASTM standard D 6400-99 (Guide for assessing the Compostability of Environmentally Degradable Plastics).
  

• Proposing a FP7 project;
• Organizing an international conference on environmental chemistry field - chemical and biochemical techniques for promoting the local research;
• Exchange of results and experience in environmental chemistry field by organizing a workshop to harmonize the Romanian regulations with the international ones;
• Participatingat training sessions with the purpose toprepare the project proposals for European programs, especially FP7;
• Organizing work visits of high-value scientific personalities from Europe;
• Closing international research agreements in environmental chemistry field.
  

• to significantly improve the diagnosis, clinical and imaging attitude, within the muscular and bone illnesses in child and in young adult.

• assessment of trace elements in food chain traceability / soil-plant relationship in Baia Mare, Cluj, Timisoara respectively;
• characterize of soil pollution level depending on the real crossing of trace elements from soil to plants.
  

• identification and implementation of evolve algorithms;
• theoretical contributions to the extension of nonlinear robust regulation;
• creating the necessary equipment for control and validation of the viability / improvement of control algorithms for their application to specified plant at INCDTIM Cluj-Napoca.
  

• developing an innovative treatment system by individualized laparoscopic cryoablation of the localized kidney tumors, using computerized simulation on 3D reconstructed model.

 APELL objectives:

• to obtain advanced methods and solutions for risk assessment in environmental science and engineering;
• to obtain framework plans for risk mitigation; 
• to obtain emergency management plan in case of disaster.

GISAR objectives:

• to identify and analyze the main risks that threaten the population within the built area;
• to identify the main risk areas;
• to elaborate some “Risk area maps” which will be used as a planning tool within the urban planning policies;
• to establish correlation between the present distribution of functional localities areas and the spatial distribution of risk areas, to highlight the existing situation;
• to integrate the results in the urban planning policies.
  

• supporting the implementation of informatic data management solutions for healthcare data at the Romanian healthcare level, through conceiving, developing and promoting a so called Electronic Health Record - EHR ("Dosar Electronic de Sanatate al Patientului – DESP").

• to develop an original technique for quantifying the qualitative information offered by ultrasonic elastography and for correlating this information with the data obtained by native three-dimensional angioultrasonography and by magnetic resonance with contrast medium, aiming to detect the stage of the disease and to monitor the evolution of breast cancer patients.

• a cognitive-behavioural psychological intervention to reduce the pain and distress for life quality improvement on short and long term, after a surgical intervention;
• treatment and diagnosis guide based on a clear, logical and simple algorithm for the therapeutical evaluation and behaviour of patients with critical ischemia;
• setting up a National Register and a national integrated network for these patients;
• articles in journals of high impact;
• PC7 project proposal.
  

• the elaboration of a personalized treatment scheme, in the antiepileptic treatment, a scheme that will take notice of the individual farmacogenomic parameters.

• developing strategies for early detection, diagnosis and monitoring of people with high risk of psychotic episode;
• these strategies facilitate, at first psychotic episode, the prevention of psychosis expression by attenuating its impact, increasing the life quality of people affected, family, community, reducing morbidity, mortality, direct costs but especially the indirect costs involving these diseases and their long evolution.
  

• the creation of an e-learning platform using the virtual models in hepatic laparoscopicsurgery;
• development of the system of e-learning;
• accessibility of this system at a world wide level which will integrate learning, research and evaluation; 
•  forming young specialists with a competence in the hepatic laparoscopic surgery, creating a collaboration between the centers of research in this domain, publishing scientific articles in the journals of their specialty and presentations of the work results at international scientific meetings;
• initiation and then application at a large scale of a program of training and research in the field of hepatic laparoscopic surgery, which will be of use for young researchers and also counting as a continuous medical education.
  

• the development of innovative techniques for the application of modern non-invasive diagnostic imaging techniques, with a view to transferring results from research to clinical practice;
• the development of clinical applications of non-invasive highly-technical methods, which will allow an increased diagnostic accuracy and will reduce the duration and cost of diagnosis, by non-invasive techniques.
  

• prospective evaluation of the intraductal echography accuracy in the diagnosis of malignant biliary stenosis;
• evaluation of proangiogenic factors with role of tumor markers in the structural and functional genomics of malignant biliary stenosis by microarray technology and protein array type;
• development and optimization of malignant biliary tumors treatment.
  

• obtaining new, modern, nonconventional methods for detecting low concentrations of the estrogen hormonal compounds, their metabolites and of some xenobiotic hormonomimetic compounds in water sources;
• research study on the influence of different methods of water treatment upon the hormonal compounds with estrogenic action.
  

• the elaboration of a innovative treatment protocol in the traumatic medullary lesions, which should include calpaine inhibitors and angiogenesis factors, which promotes the survival of the neurons, oligodendrocytes and angiogenesis, resulting in functional recovery of traumatic medullary lesions;
• the accomplishment of applicable experimental models for the study of synergic influences of calpaine inhibitors + vascular trophic factors;
• the clinical study of this well-defined pathology with performing technical means, on carefully selected cases.
  

• optimizating the urban mobility, in condition of increases safety in areas of intense circulation in agreement with specific characteristics of vehicle dynamics who correspond exploitation in urban environment;
• developing researches regarding the realization of applicable models for optimization and monitoring of the parking lots, as a permanent sources of traffic congestion and optimization of corridors for passenger urban transportation and a modality to discourage the individual displacement, who represent an acute problem in crowded centres.
  

• multi-proxy, geological, hydrological, water chemistry (heavy metals, organic pollutants and micropollutants) and faunistic studies and their integration in an unitary evaluation system;
• estimating the pollution degree of the aquifer waters and sediments in time and space, which will be performed after the integration of the obtained data by the interpretation of the laboratory data;
• monitoring biological communities, and water and sediments chemistry in polluted and uncontaminated zones (repeated sampling and processing of samples in laboratory);
• determining the superoxid dismutase (SOD) activity as heavy metal-induced oxidative stress in crustaceans tissues and organic fluids;
• developing the sensors for heavy metals that will transmit the information in GRID system;
• constructing the MODEL-ACVASUB;
• results dissemination (e.g. articles, communications, web page, course supports, workshop).
  

• to develop an informational system and to create a national agro-tourism instrument in order to present agro-touristic virtual environments, allowing tourists from all over the world to use it.

• identification and synthesis of some of the functional nanostructure groups;
• introduction of the p53 gene sequence inside the nanostructure cavity;
• performing in vitro and in vivo biological tests upon hepatic tumors;
• realization of an experimental model of hepatic tumor.
  

• dissemination of the obtained results through an international symposium and an intensive course dedicated to the family physicians regarding new modalities to treat chronic conditions from neurogastroeneterology field, aiming to develop a customized strategy patient-oriented, from prevention to diagnosis and treatment .

• the development of new surgical methods and techniques adapted to the needs of bionanostructures with multifunctional properties, obtained by specific methods of molecular or colloidal auto-assembly.

• to establish the molecular risk of metastatic disease in patients already diagnosed with pancreatic cancer, with prognostic role;
• to identify certain biomarkers for detecting early pancreatic cancer;
• to stratify the malignancy risk according to the proteomic modifications at the patients with risk factors for pancreatic cancer (chronic pancreatitis, diabetes mellitus);
• a better understanding of the pancreatic carciogenesis, with the perspective of precise molecular therapeutic targets.
  

• to exploit the competences from different fields in order to develop innovative solutions with outstanding performances and advanced control systems based in the concept and characteristics of parallel robots in order to offer efficient solutions for applications in the field of minimally invasive surgery.

• supply and facilitate the information changes, results and knowledge transfer;
• capitalize and increase the Romanian competencies and research potential;
• interconnection and communication between internal research centres and international centres;
• helping participation and integration in international projects and research networks.
  

• the investigation of the correlation between medical variables (the type and the gravity of the periodontal defect, the tooth type, the gingivo-periodontal phenotype) and the psychological ones (the types of cognitions, the level of distress, the expectancies);
• the improvement of a therapeutic algorithm centered on the patient;
• the calculation of the success rate of surgical procedures;
• the calculation of a secondary root coverage index;
• the quantification of some parameters of patient outcome;
• data base realization , which will allow the realization of an informational area in muco-gingical surgery field, with further extension in other very actual research areas;
• the transfer of the results of the project associated with the treatment of periodontal diseases, for elaborating of an evidence based strategy centered on the patient;
• the dissemination of some interventional algorithms towards other working groups (academical groups, dentists), at the Europeans standards.
  

• to achieve a program which can be applied in various units requiring the appreciation of the biological age and of the real brain performance, solely based on imaging data, without applying invasive methods, by simply obtaining morphologic indexes obtained by MRI or CT.

• elaboration of conceptual models and applicable techniques in case of bioremediation technologies of soils contaminated with heavy metals, sulfur dioxide, petroleum products, etc;
• use of a modern scientific methodology for risk and impact assessment of activities specific to metallurgical industry upon soils;
• identification and development of some micro-organisms capable of ensuring the biodegradation of pollutants from the contaminated soils;
• development of an innovative technology for biological treatment – on-site and off-site – of the contaminated soils;
• elaboration of a remediation technology of soils contaminated by the activities specific to metallurgical industry, based on the biological treatment – on-site and off-site – of contaminated soils.
  

• modernizing of food production;
• obtaining valuable products conforming to the food security
  principles;
• developing a new methodology, efficient and nonpolluting, for valorification of some waste waters from food industry for obtaining valuable products;
• developing an enzymatic methodology, ecological and economical for reducing the production costs of process for obtaining floury pasta;
• a patent;
• PC 7;
• project proposal.
  

• the research, design and implementation of an experimental model of a ¹³C isotope separation plant by cryogenic distillation of CO and the obtaining of data to enable further technological development to achieve a productive plant.

• inventorying, evaluating quantitatively and qualitatively the polluting elements in their territorial distribution, favored by natural hazards (landslides, floods).

• elaborating techniques that will improve and increase safety in insuring food quality on the entire food chain: staples, final product.

• the accomplishment of a complex research regarding the soil pollution, especially of those that are neighboring the oil exploitation and refinery stations (pollutant type, pollution degree, pollution depth);
• the determination in real time by fluorescence of the soil oil contaminants;
• the adoption of strategies, necessary measures and methods for the ecological rehabilitation so as to increase the value of the land and its use in the community benefit;
• the rehabilitation using a bioremediation biological method of a characteristic pilot area from a contaminated area.
  

• studies, analyses and documentation for the methodology elaboration;
  elaborating a methodology for the monitoring of food supplements starting with the raw materials and ending with the product;
• experimenting the methodology;
• creating an unitary database which will contain information needed to establish an quality management system of food supplements useful both on governmental level and for industry;
• dissemination of results: scientific papers, scientific communications, web pages, workshop.
  

• to investigate the pharmacogenomic status of the patients, from both geno- andphenotypic point of view;
• to reveal the polymorphism of the CYP2C9 and VKORC1 genes, and alsoof the genes involved in the thrombophilia phenomenon (Factor V Leiden, FII G20210A, PAI-1 4G/5G, MTHFR C677T and A1298C) and the possible relationship between the presence of these polymorphisms and the response to acenocumarol treatment;
• to adapt the acenocumarol treatment to the individual genetic constellation of the individuals, through a multidisciplinary approach, which will increase the medical act’s and the patient’s life quality, achieving a positive costs to benefits ratio and elaborating a personalized treatment.